Head-to-Head Specification Audit
Salesforce vs Epic Systems
Enterprise Sales Teams · Global
Healthcare Software
Epic Systems
Enterprise Electronic Health Records · United States
Visit Epic Systems →Specification Matrix
| Metric | Salesforce | Epic Systems |
|---|---|---|
| Starting Price | $25/moBetter | $1000000/mo |
| API Rate Limit | 1000 req/minBetter | 200 req/min |
| Target Country | Global | United States |
| Category | CRM | Healthcare Software |
| Compliance | GDPR, CCPA, POPIA, SOC2, ISO27001, FedRAMP | HIPAA, ONC, SOC2, HL7-FHIR, FDA-SaMD |
| Hosting Regions | US-East, EU-West, AP-Southeast, AU-East | US-East, US-West |
| Native Integrations | 7 listedBetter | 5 listed |
Salesforce — Key Specs
- ✓Einstein AI forecasting surfaces at-risk deals before they slip
- ✓AppExchange has 7,000+ certified B2B integrations
- ✓POPIA and GDPR data governance controls built into Org settings
- ✓Customisable objects and flows handle any sales process complexity
Epic Systems — Key Specs
- ✓Largest EHR market share (35%+ of US hospital beds)
- ✓MyChart patient portal with 200M+ registered patients
- ✓Epic AI (Cosmos) — largest real-world clinical dataset for AI training
- ✓ONC-certified, HIPAA, HL7 FHIR R4 compliant
Frequently Asked Questions
What is cheaper, Salesforce or Epic Systems?+
Salesforce starts at $25/mo, which is lower than Epic Systems at $1000000/mo.
Which tool is better for compliance — Salesforce or Epic Systems?+
Both support SOC2. Salesforce additionally supports GDPR, CCPA, POPIA, ISO27001, FedRAMP. Epic Systems additionally supports HIPAA, ONC, HL7-FHIR, FDA-SaMD.
Is Salesforce or Epic Systems compliant with South Africa's POPIA?+
Salesforce supports POPIA compliance. Epic Systems does not list POPIA as a supported framework.
Which has a higher API rate limit — Salesforce or Epic Systems?+
Salesforce has a higher API rate limit at 1000 requests per minute. Salesforce: 1000 req/min. Epic Systems: 200 req/min.
Which tool is better suited for Global?+
Salesforce is evaluated for Enterprise Sales Teams in Global with hosting regions: US-East, EU-West, AP-Southeast, AU-East. Epic Systems has hosting regions: US-East, US-West. For data residency in Global, check each vendor's data processing agreements.
Data last verified: 26 June 2026
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