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Independent directory. VektorIndex is not affiliated with or sponsored by any third-party vendor. (VektorIndex's own developer tools are also listed, identified by name.) All specifications are sourced from official vendor documentation and are not independently audited.
Note: Epic Systems (Healthcare Software) and Zoho CRM (CRM) are in different software categories. This comparison may be relevant if you are evaluating them for overlapping use cases. For same-category comparisons, browse Healthcare Software tools.

Head-to-Head Specification Audit

Epic Systems vs Zoho CRM

Enterprise Electronic Health Records · United States

Healthcare Software

Epic Systems

Enterprise Electronic Health Records · United States

Visit Epic Systems

CRM

Zoho CRM

CRM for SMB — Africa & India Focused · South Africa

Visit Zoho CRM

Specification Matrix

MetricEpic SystemsZoho CRM
Starting PriceCustom pricing$14/mo
API Rate Limit200 req/minBetter100 req/min
Target CountryUnited StatesSouth Africa
CategoryHealthcare SoftwareCRM
Compliance (vendor-stated)HIPAA, ONC, SOC2, HL7-FHIR, FDA-SaMDGDPR, POPIA, SOC2
Hosting RegionsUS-East, US-WestUS-East, EU-West, IN-Central
Native Integrations5 listed6 listedBetter

Epic Systems — Key Specs

Vendor-stated
  • Largest EHR market share (35%+ of US hospital beds)
  • MyChart patient portal with 200M+ registered patients
  • Epic AI (Cosmos) — largest real-world clinical dataset for AI training
  • ONC-certified, HIPAA, HL7 FHIR R4 compliant

Zoho CRM — Key Specs

Vendor-stated
  • Best value CRM for South African companies — ZAR pricing available
  • Zia AI: sales predictions, anomaly detection, next best time to contact
  • POPIA-compliant: data residency and DPA options for ZA companies
  • Free tier: 3 users, core CRM features

Frequently Asked Questions

Which is lower-priced, Epic Systems or Zoho CRM?+

Epic Systems uses custom pricing. Zoho CRM starts at $14/mo. Contact Epic Systems directly for a quote.

Which compliance frameworks do Epic Systems and Zoho CRM list?+

Both list SOC2 in their vendor documentation. Epic Systems additionally lists HIPAA, ONC, HL7-FHIR, FDA-SaMD. Zoho CRM additionally lists GDPR, POPIA. These are vendor-stated frameworks. VektorIndex has not independently audited these claims.

Does Epic Systems or Zoho CRM list POPIA as a supported compliance framework?+

Zoho CRM lists POPIA (Protection of Personal Information Act) as a supported compliance framework per its vendor documentation. VektorIndex has not independently verified this claim. South African organisations should request the vendor's current Data Processing Agreement and confirm data residency settings before processing personal information. Epic Systems does not list POPIA as a supported compliance framework in its public documentation. Contact the vendor to confirm their position before processing South African personal information.

Which has a higher documented API rate limit — Epic Systems or Zoho CRM?+

Epic Systems has a higher documented API rate limit at 200 req/min versus Zoho CRM at 100 req/min.

Which data hosting regions do Epic Systems and Zoho CRM support?+

Epic Systems lists hosting regions: US-East, US-West. Zoho CRM lists hosting regions: US-East, EU-West, IN-Central. For data residency requirements in United States, confirm exact region configuration directly with each vendor.

Data last updated: 29 August 2026Sourced from official vendor documentation. Not independently audited. Report incorrect information

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