Head-to-Head Specification Audit
Zendesk vs Epic Systems
Mid-Market & Enterprise Support Teams · Global
Healthcare Software
Epic Systems
Enterprise Electronic Health Records · United States
Visit Epic Systems →Specification Matrix
| Metric | Zendesk | Epic Systems |
|---|---|---|
| Starting Price | $19/mo | Custom pricing |
| API Rate Limit | 200 req/minTie | 200 req/minTie |
| Target Country | Global | United States |
| Category | Customer Support | Healthcare Software |
| Compliance (vendor-stated) | CCPA, GDPR, HIPAA, ISO27001, SOC2 | HIPAA, ONC, SOC2, HL7-FHIR, FDA-SaMD |
| Hosting Regions | US-East, US-West, EU-West, AP-Southeast, AU-East | US-East, US-West |
| Native Integrations | 6 listedBetter | 5 listed |
Zendesk — Key Specs
Vendor-stated- ✓Industry standard for enterprise customer support — 100,000+ businesses
- ✓AI Agents handle tier-1 support automatically — deflects 40%+ of tickets
- ✓Sunshine Platform allows custom CRM objects and workflows
- ✓Marketplace with 1,500+ apps and integrations
Epic Systems — Key Specs
Vendor-stated- ✓Largest EHR market share (35%+ of US hospital beds)
- ✓MyChart patient portal with 200M+ registered patients
- ✓Epic AI (Cosmos) — largest real-world clinical dataset for AI training
- ✓ONC-certified, HIPAA, HL7 FHIR R4 compliant
Frequently Asked Questions
Which is lower-priced, Zendesk or Epic Systems?+
Epic Systems uses custom pricing. Zendesk starts at $19/mo. Contact Epic Systems directly for a quote.
Which compliance frameworks do Zendesk and Epic Systems list?+
Both list HIPAA, SOC2 in their vendor documentation. Zendesk additionally lists CCPA, GDPR, ISO27001. Epic Systems additionally lists ONC, HL7-FHIR, FDA-SaMD. These are vendor-stated frameworks. VektorIndex has not independently audited these claims.
Which has a higher documented API rate limit — Zendesk or Epic Systems?+
Both Zendesk and Epic Systems have the same documented API rate limit of 200 requests per minute. Verify current limits on each vendor's developer documentation.
Which data hosting regions do Zendesk and Epic Systems support?+
Zendesk lists hosting regions: US-East, US-West, EU-West, AP-Southeast, AU-East. Epic Systems lists hosting regions: US-East, US-West. For data residency requirements in Global, confirm exact region configuration directly with each vendor.
Data last updated: 29 August 2026 — Sourced from official vendor documentation. Not independently audited. Report incorrect information
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