Head-to-Head Specification Audit
Epic Systems vs Zendesk
Enterprise Electronic Health Records · United States
Healthcare Software
Epic Systems
Enterprise Electronic Health Records · United States
Visit Epic Systems →Specification Matrix
| Metric | Epic Systems | Zendesk |
|---|---|---|
| Starting Price | Custom pricing | $19/mo |
| API Rate Limit | 200 req/minTie | 200 req/minTie |
| Target Country | United States | Global |
| Category | Healthcare Software | Customer Support |
| Compliance (vendor-stated) | HIPAA, ONC, SOC2, HL7-FHIR, FDA-SaMD | CCPA, GDPR, HIPAA, ISO27001, SOC2 |
| Hosting Regions | US-East, US-West | US-East, US-West, EU-West, AP-Southeast, AU-East |
| Native Integrations | 5 listed | 6 listedBetter |
Epic Systems — Key Specs
Vendor-stated- ✓Largest EHR market share (35%+ of US hospital beds)
- ✓MyChart patient portal with 200M+ registered patients
- ✓Epic AI (Cosmos) — largest real-world clinical dataset for AI training
- ✓ONC-certified, HIPAA, HL7 FHIR R4 compliant
Zendesk — Key Specs
Vendor-stated- ✓Industry standard for enterprise customer support — 100,000+ businesses
- ✓AI Agents handle tier-1 support automatically — deflects 40%+ of tickets
- ✓Sunshine Platform allows custom CRM objects and workflows
- ✓Marketplace with 1,500+ apps and integrations
Frequently Asked Questions
Which is lower-priced, Epic Systems or Zendesk?+
Epic Systems uses custom pricing. Zendesk starts at $19/mo. Contact Epic Systems directly for a quote.
Which compliance frameworks do Epic Systems and Zendesk list?+
Both list HIPAA, SOC2 in their vendor documentation. Epic Systems additionally lists ONC, HL7-FHIR, FDA-SaMD. Zendesk additionally lists CCPA, GDPR, ISO27001. These are vendor-stated frameworks. VektorIndex has not independently audited these claims.
Which has a higher documented API rate limit — Epic Systems or Zendesk?+
Both Epic Systems and Zendesk have the same documented API rate limit of 200 requests per minute. Verify current limits on each vendor's developer documentation.
Which data hosting regions do Epic Systems and Zendesk support?+
Epic Systems lists hosting regions: US-East, US-West. Zendesk lists hosting regions: US-East, US-West, EU-West, AP-Southeast, AU-East. For data residency requirements in United States, confirm exact region configuration directly with each vendor.
Data last updated: 29 August 2026 — Sourced from official vendor documentation. Not independently audited. Report incorrect information
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