Head-to-Head Specification Audit
Epic Systems vs Salesforce
Enterprise Electronic Health Records · United States
Healthcare Software
Epic Systems
Enterprise Electronic Health Records · United States
Visit Epic Systems →Specification Matrix
| Metric | Epic Systems | Salesforce |
|---|---|---|
| Starting Price | $1000000/mo | $25/moBetter |
| API Rate Limit | 200 req/min | 1000 req/minBetter |
| Target Country | United States | Global |
| Category | Healthcare Software | CRM |
| Compliance | HIPAA, ONC, SOC2, HL7-FHIR, FDA-SaMD | GDPR, CCPA, POPIA, SOC2, ISO27001, FedRAMP |
| Hosting Regions | US-East, US-West | US-East, EU-West, AP-Southeast, AU-East |
| Native Integrations | 5 listed | 7 listedBetter |
Epic Systems — Key Specs
- ✓Largest EHR market share (35%+ of US hospital beds)
- ✓MyChart patient portal with 200M+ registered patients
- ✓Epic AI (Cosmos) — largest real-world clinical dataset for AI training
- ✓ONC-certified, HIPAA, HL7 FHIR R4 compliant
Salesforce — Key Specs
- ✓Einstein AI forecasting surfaces at-risk deals before they slip
- ✓AppExchange has 7,000+ certified B2B integrations
- ✓POPIA and GDPR data governance controls built into Org settings
- ✓Customisable objects and flows handle any sales process complexity
Frequently Asked Questions
What is cheaper, Epic Systems or Salesforce?+
Salesforce starts at $25/mo, which is lower than Epic Systems at $1000000/mo.
Which tool is better for compliance — Epic Systems or Salesforce?+
Both support SOC2. Epic Systems additionally supports HIPAA, ONC, HL7-FHIR, FDA-SaMD. Salesforce additionally supports GDPR, CCPA, POPIA, ISO27001, FedRAMP.
Is Epic Systems or Salesforce compliant with South Africa's POPIA?+
Salesforce supports POPIA compliance. Epic Systems does not list POPIA as a supported framework.
Which has a higher API rate limit — Epic Systems or Salesforce?+
Salesforce has a higher API rate limit at 1000 requests per minute. Epic Systems: 200 req/min. Salesforce: 1000 req/min.
Which tool is better suited for United States?+
Epic Systems is evaluated for Enterprise Electronic Health Records in United States with hosting regions: US-East, US-West. Salesforce has hosting regions: US-East, EU-West, AP-Southeast, AU-East. For data residency in United States, check each vendor's data processing agreements.
Data last verified: 26 June 2026
Related Healthcare Software Comparisons
Is this your tool?
Claim or upgrade your VektorIndex listing
Get a Verified badge, add your own specs, and appear at the top of comparison pages.