Head-to-Head Specification Audit
Epic Systems vs Personio
Enterprise Electronic Health Records · United States
Healthcare Software
Epic Systems
Enterprise Electronic Health Records · United States
Visit Epic Systems →Specification Matrix
| Metric | Epic Systems | Personio |
|---|---|---|
| Starting Price | Custom pricing | $4/mo |
| API Rate Limit | 200 req/minBetter | 80 req/min |
| Target Country | United States | European Union |
| Category | Healthcare Software | HR & Recruiting AI |
| Compliance (vendor-stated) | HIPAA, ONC, SOC2, HL7-FHIR, FDA-SaMD | GDPR, SOC2 |
| Hosting Regions | US-East, US-West | EU-West, EU-Central |
| Native Integrations | 5 listed | 6 listedBetter |
Epic Systems — Key Specs
Vendor-stated- ✓Largest EHR market share (35%+ of US hospital beds)
- ✓MyChart patient portal with 200M+ registered patients
- ✓Epic AI (Cosmos) — largest real-world clinical dataset for AI training
- ✓ONC-certified, HIPAA, HL7 FHIR R4 compliant
Personio — Key Specs
Vendor-stated- ✓All-in-one HR for European SMBs — payroll, recruiting, time tracking
- ✓GDPR-native: EU data residency, automated deletion, consent management
- ✓Strong German market with DATEV payroll integration
- ✓AI recruiting assistant launching 2026
Frequently Asked Questions
Which is lower-priced, Epic Systems or Personio?+
Epic Systems uses custom pricing. Personio starts at $4/mo. Contact Epic Systems directly for a quote.
Which compliance frameworks do Epic Systems and Personio list?+
Both list SOC2 in their vendor documentation. Epic Systems additionally lists HIPAA, ONC, HL7-FHIR, FDA-SaMD. Personio additionally lists GDPR. These are vendor-stated frameworks. VektorIndex has not independently audited these claims.
Which has a higher documented API rate limit — Epic Systems or Personio?+
Epic Systems has a higher documented API rate limit at 200 req/min versus Personio at 80 req/min.
Which data hosting regions do Epic Systems and Personio support?+
Epic Systems lists hosting regions: US-East, US-West. Personio lists hosting regions: EU-West, EU-Central. For data residency requirements in United States, confirm exact region configuration directly with each vendor.
Data last updated: 29 August 2026 — Sourced from official vendor documentation. Not independently audited. Report incorrect information
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