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Head-to-Head Specification Audit

Epic Systems vs AWS

Enterprise Electronic Health Records · United States

Healthcare Software

Epic Systems

Enterprise Electronic Health Records · United States

Visit Epic Systems

Cloud Hosting & Edge

AWS

Enterprise & SaaS Developers · Global

Visit AWS

Specification Matrix

MetricEpic SystemsAWS
Starting Price$1000000/moCustomBetter
API Rate Limit200 req/minN/A
Target CountryUnited StatesGlobal
CategoryHealthcare SoftwareCloud Hosting & Edge
ComplianceHIPAA, ONC, SOC2, HL7-FHIR, FDA-SaMDGDPR, CCPA, POPIA, SOC2, ISO27001, HIPAA, FedRAMP
Hosting RegionsUS-East, US-WestUS-East, US-West, EU-West, AP-Southeast, AU-East, AF-South-ZA
Native Integrations5 listed7 listedBetter

Epic Systems — Key Specs

  • Largest EHR market share (35%+ of US hospital beds)
  • MyChart patient portal with 200M+ registered patients
  • Epic AI (Cosmos) — largest real-world clinical dataset for AI training
  • ONC-certified, HIPAA, HL7 FHIR R4 compliant

AWS — Key Specs

  • Cape Town region (af-south-1) provides local ZA data residency for POPIA compliance
  • 200+ cloud services covering compute, storage, AI, databases, and IoT
  • 99.99% uptime SLA on core services including S3, RDS, and EC2
  • Spot Instances reduce compute costs by up to 90% for fault-tolerant workloads

Frequently Asked Questions

What is cheaper, Epic Systems or AWS?+

AWS starts at $0/mo, which is lower than Epic Systems at $1000000/mo.

Which tool is better for compliance — Epic Systems or AWS?+

Both support HIPAA, SOC2. Epic Systems additionally supports ONC, HL7-FHIR, FDA-SaMD. AWS additionally supports GDPR, CCPA, POPIA, ISO27001, FedRAMP.

Is Epic Systems or AWS compliant with South Africa's POPIA?+

AWS supports POPIA compliance. Epic Systems does not list POPIA as a supported framework.

Which tool is better suited for United States?+

Epic Systems is evaluated for Enterprise Electronic Health Records in United States with hosting regions: US-East, US-West. AWS has hosting regions: US-East, US-West, EU-West, AP-Southeast, AU-East, AF-South-ZA. For data residency in United States, check each vendor's data processing agreements.

Data last verified: 26 June 2026

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